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KMID : 0378019930360050047
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New Medical Journal
1993 Volume.36 No. 5 p.47 ~ p.52
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Ocular Hypotensives and Early Ocular Hypertension After Cataract Surgery
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Abstract
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During -the immediate postoperative period following cataract surgery, intraocular pressure (IOP) often rises significantly to impede the ocular circulation and threaten the visual function of the optic disc in some patients with vulnerable ocular disease such as advanced glaucoma. Some kind of ocular hypotensives were reported to be´ effective for preventing or aborting the immediate -postoperative IOP rise. However, they were not evaluated systemically for the possibility to prevent the immediate postoperative IOP rise.
in this study the immediate postoperative change in IOP were prospectively studied in 65 patients after phacoemusification and posterior-chamber lens implantation, according to preoperative, operative and postoperative managements for decreasing IOPs. Sixty-five eyes were randomly assigned to four group : group 1 as a control group consisting of 20 eyes in which no ocular hypotensives were administered ; group 2 consisting of 15 eyes in which 500mg of diamox (acetazolamide) was administered orally 90 minutes before operation ; group 3-consisting of 15 eyes in which 0.1 ml of carbachol 0.01% was infused into anterior chamber during operation ; group 4 consisting of 15 eyes in which pilogel (pilocarpine ointment) was applied at the end of surgery. A slit-lamp and applanation tonometry were done postoperative 6 hour, 1, 2, 3 day, 1, 2week, the first and second month.
Preoperative baseline IOP means were no different between four groups (p>0.05). An average postoperative 6-hour and 12-hour IOP of group 1 increased by 6.5mmHg and 3.8mmHg comparing to the baseline mean IOP (p<0.05). However there was no statistically significant IOP rise in group 2, 3 and 4 (p>0.05).
From this-study, it was concluded that administrations of preoperative acetazolamide, operative carbachol and postoperative pilogel resulted in a reduction of immediate postoperative IOP rise.
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